In normal doses paracetamol has no major side effects, but in large doses it may cause liver damage.
After being taken by mouth Paracetamol is rapidly absorbed by (GI) tract (although absorption through the stomach is negligible)
After four hours the concentration is usually less than 10 µg/mL.
After four hours the concentration is usually less than 10 µg/mL.
The first signs of a paracetamol include nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach due to hepatic damage(large doses),
dark urine, and yellowing of your skin or the whites of your eyes.
dark urine, and yellowing of your skin or the whites of your eyes.
Untreated overdose can lead to death within days due to liver failure.
Treatment is given for removing the paracetamol from the body and replenishing glutathione.
Treatment is given for removing the paracetamol from the body and replenishing glutathione.
Activated charcoal helps to reduce absorption when given immediately of paracetamol ingestion.
antidote given for paracetamol over dose is N-acetylcysteine.
antidote given for paracetamol over dose is N-acetylcysteine.
No comments:
Post a Comment